NEW STUDIES COMPARING THE ADVANCED APTOS POLYCAPROLACTONE (PCL) THREADS WITH BEAUTY POLYDIOXANONE (PDO) THREADS
Studies below describe significant scientific advantages of polycaprolactone (PCL) threads over Polydioxanone (PDO) threads.
PCL Threads (Aptos Threads) Show Significant Skin Rejuvenation and Wrinkle Reduction

Researchers evaluated the efficacy of polycaprolactone (PCL) threads compared to other commercial threads used for lifting and wrinkle reduction. The findings of the study were published in the Journal of Cosmetic Dermatology (January 9, 2021).
Thirty six-week-old, male, SKH-1, hairless mice were randomized to one of five groups: New PCL (Glo-One), PCL (Ultra-V), PDO (Meta Biomed), PLLA (Apromedion) or control. All threads were 50 mm in length and 0.3 mm in diameter. The researchers implanted the threads at either side of the spine of each mouse.
Biopsy specimens were obtained at one, four and eight weeks, and examined using hemotoxylin and eosin (H&E) and Herovici’s stain. Immunoblot analysis was also performed using primary antibody for collagen type III and transforming growth factor-β (TGF-β ) and visualised by chemiluminescence and densitometric quantification. Lastly, skin replicas were used to calculate the total wrinkle area.
All thread types significantly induced collagen at all time points. In the new PCL and pre-existing PCL groups, neocollagenesis was significantly increased by 50% at eight weeks compared to PDO and PLLA threads. Additionally, new-PCL-implanted mice showed a significant increase in collagen type III and TGF-β expression at eight weeks. The number of inflammatory cells was also increased in the skin of PCL-implanted mice, and wrinkles were reduced by 20% in the new PCL group, at eight weeks.
TALK TO THE MD COSMEDICAL SOLUTIONS SKIN CLINIC TEAM ABOUT APTOS THREAD FACELIFTS
Learn about the differences between medical Aptos Thread and beauty PDO Threads
Consultations with Dr Buddy Beaini and our medical consultants are comprehensive, ensuring personalised treatment plans aligned with your aesthetic goals and medical history. With a focus on safety and efficacy, MD Cosmedical Solutions Cosmetic Clinics has provided reputable cosmetic care since 2001, offering non-surgical procedures with minimal risks and superior results.
Embark on a journey to a rejuvenated appearance with the Aptos Threads Facelift at MD Cosmedical Solutions. Schedule a consultation to discover the antiaging non-surgical facelift benefits of this innovative procedure. MD Cosmedical Solutions Cosmetic Clinics are located in Sydney CBD, Wahroonga and Canberra.
Administered exclusively by accredited physicians, Aptos Threadlifts stand apart from non-performing PDO thread options. Only experienced doctors licensed and extensively trained in the Aptos Threads Facelift technique are authorized to perform these procedures. Patients are advised to do their research into the best threadlifting options, and the experience of the medical practitioner.
All cosmetic medical procedures may have small risks or variable results, and some patients may not be suitable for certain procedures. However, the usual risks of traditional plastic surgery or general anesthesia does not exist as these procedures are non-surgical.
We offer free consultations, and MD Cosmedical Solutions Cosmetic Clinic locations include Sydney CBD, Wahroonga (OFF M1), and Canberra (Barton). Please feel free to contact us to schedule an appointment or for any further information you may require.
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